| Product Number |
OAAF01933 |
| Product Page |
www.avivasysbio.com/snca-antibody-oaaf01933.html |
| Name |
SNCA Antibody (OAAF01933) |
| Molecular Weight |
14 kDa |
| NCBI Gene Id |
6622 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Gene Full Name |
synuclein alpha |
| Alias Symbols |
alpha-synuclein;I+/--synuclein;NACP;non A-beta component of AD amyloid;Non-A beta component of AD amyloid;Non-A4 component of amyloid precursor;PARK1;PARK4;PD1;synuclein alpha-140;synuclein, alpha (non A4 component of amyloid precursor);truncated alpha synuclein. |
| Product Format |
Liquid |
| Reference |
Eirene Kontopoulos, Hum. Mol. Genet., Oct 2006; 15: 3012 - 3023.
Heather Snyder, J. Biol. Chem., Mar 2005; 280: 7562 - 7569.
Wanli W. Smith, J. Neurosci., Jun 2005; 25: 5544 - 5552.
Yuxin Fan, Hum. Mol. Genet., Oct 2006; 15: 3002 - 3011. |
| Description of Target |
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. |
| Reconstitution and Storage |
-20°C |
| Datasheets/Manuals |
Printable datasheet for SNCA Antibody (OAAF01933) |
| Specificity |
Synuclein-pan antibody detects endogenous levels of total Synuclein protein. |
| Application Info |
WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:5000 |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human Synuclein. |
| Dilution |
The optimal working dilution should be determined by the end user. |
| Formulation |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot ID |
P37840 |
| Protein Name |
Alpha-synuclein |
| Protein Accession # |
NP_000336.1 |
| Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Gene Symbol |
SNCA |
| Predicted Species Reactivity |
Human|Mouse|Rat |
| Application |
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
| Image 1 | human brain tissue
 | Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Synuclein-pan Antibody. The picture on the right is treated with the synthesized peptide. |
| | Image 2 | rat heart cells
 | Western blot analysis of extracts from rat heart cells, using Synuclein-pan Antibody. The lane on the right is treated with the synthesized peptide. |
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