KIP2 Antibody - N-terminal region (OAAB17545)

• Product Number: OAAB17545
• Name: KIP2 Antibody - N-terminal region (OAAB17545)
• Molecular Weight: 21644 Da
• Isotype: Ig
• NCBI Gene Id: 10518
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: KIP2, USH1J, DFNB48
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: KIP2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity)
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
• Immunogen: This KIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human KIP2.
• Additional Information: Cellular Location: Photoreceptor inner segment (By similarity). Note=Expressed in inner and outer segments of photoreceptor cells, as well as in the pigmented epithelium. Also observed in the inner and outer plexiform layers and in the ganglion cell layer (By similarity)
  Tissue Location: Ubiquitous.
• Uniprot ID: O75838
• Protein Name: Calcium and integrin-binding family member 2
• Protein Accession #: NP_006374.1
• Gene Symbol: CIB2
• Predicted Species Reactivity: Human
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Human
• Image 1: Ramos
  
  Western blot analysis of anti-KIP2 Pab (Cat. # OAAB17545) in Ramos cell line lysate (35ug/lane). KIP2(arrow) was detected using the purified Pab (1:60 dilution)
• Image 2: breast carcinoma
  
  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.