MAP3K13 Antibody - C-terminal region (Phospho-S869) (OAAB17367)

• Product Number: OAAB17367
• Name: MAP3K13 Antibody - C-terminal region (Phospho-S869) (OAAB17367)
• Molecular Weight: 108296 Da
• Isotype: Ig
• NCBI Gene Id: 9175
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Alias Symbols: LZK, MLK, MEKK13
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Precautions: MAP3K13 (LZK) Antibody (C-term) (S869) is for research use only and not for use in diagnostic or therapeutic procedures.
• Additional Information: Function: Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B
• Application Info: WB: 1:1000
  IHC-P: 1:10~50
• Immunogen: This MAP3K13 (LZK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 854-884 amino acids from the C-terminal region of human MAP3K13 (LZK).
• Additional Information: Cellular Location: Cytoplasm. Membrane; Peripheral membrane protein
  Tissue Location: Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas
• Uniprot ID: O43283
• Protein Name: Mitogen-activated protein kinase kinase kinase 13
• Protein Accession #: NP_001229243.1
• Gene Symbol: MAP3K13
• Predicted Species Reactivity: Human
• Application: WB, IHC
• Predicted Homology Based on Immunogen Sequence: Human
• Image 1: Human Pancreas
  
  MAP3K13 (LZK) Antibody (C-term) (S869) (Cat. # OAAB17367) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MAP3K13 (LZK) Antibody (C-term) (S869) for immunohistochemistry. Clinical relevance has not been evaluated.
• Image 2: CEM
  
  LZK Antibody (C-term) (Cat.# OAAB17367) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the LZK antibody detected the LZK protein (arrow).