| Product Number |
OAAB17045 |
| Product Page |
www.avivasysbio.com/csnk1a1-antibody-c-terminal-region-oaab17045.html |
| Name |
CSNK1A1 Antibody - C-terminal region (OAAB17045) |
| Molecular Weight |
38915 Da |
| Isotype |
Ig |
| NCBI Gene Id |
1452 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
CK1, CK1a, CKIa, HLCDGP1, PRO2975, HEL-S-77p |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB17045 |
| Additional Information |
Precautions: CSNK1A1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45' May play a role in segregating chromosomes during mitosis |
| Application Info |
IHC-P: 1:10~50
WB: 1:1000 |
| Immunogen |
This CSNK1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human CSNK1A1. |
| Additional Information |
Cellular Location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle Note=Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis |
| Uniprot ID |
P48729 |
| Protein Name |
Casein kinase I isoform alpha |
| Protein Accession # |
NP_001020276.1 |
| Gene Symbol |
CSNK1A1 |
| Predicted Species Reactivity |
Human |
| Application |
IHC |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | Human lung carcinoma
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CK1a antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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