MAGEL2 Antibody - C-terminal region (OAAB16526)

Data Sheet
 
Product Number OAAB16526
Product Page www.avivasysbio.com/magel2-antibody-c-terminal-region-oaab16526.html
Name MAGEL2 Antibody - C-terminal region (OAAB16526)
Molecular Weight 58669 Da
Isotype Ig
Host Rabbit
Clonality Polyclonal
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Alias Symbols MAGEL2, NDNL1, MAGE-like protein 2, Necdin-like protein 1, Protein nM15
Product Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Description of Target Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OAAB16526
Additional Information Precautions: MAGEL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Additional Information Function: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex
Application Info WB: 1:1000
IHC-P: 1:10~50
Immunogen This MAGEL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-529 amino acids from the C-terminal region of human MAGEL2.
Additional Information Tissue Location: Expressed in placenta, fetal and adult brain. Not detected in heart and small intestine, very low levels in fibroblasts. Not expressed in brain of a Prader-Willi patient
Uniprot ID Q9UJ55
Protein Name MAGE-like protein 2
Gene Symbol MAGEL2
Predicted Species Reactivity Human
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Human
Image 1
K562
MAGEL2 Antibody (D514) (Cat. # OAAB16526) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MAGEL2 antibody detected the MAGEL2 protein (arrow).
Image 2
Human Brain
MAGEL2 Antibody (C-term) (Cat. # OAAB16526) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MAGEL2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
 

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