| Product Number |
OAAB16504 |
| Product Page |
www.avivasysbio.com/lrp2-megalin-antibody-c-terminal-region-oaab16504.html |
| Name |
LRP2 Antibody - C-terminal region (OAAB16504) |
| Molecular Weight |
521958 Da |
| Isotype |
Ig |
| NCBI Gene Id |
4036 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
DBS, GP330, LRP-2 |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB16504 |
| Additional Information |
Precautions: LRP2 (Megalin) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid- hormone and para-thyroid-hormone-related protein release |
| Application Info |
IHC-P: 1:50~100 |
| Immunogen |
This LRP2 (Megalin) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4626-4655 amino acids from the C-terminal region of human LRP2 (Megalin). |
| Additional Information |
Cellular Location: Membrane; Single-pass type I membrane protein. Membrane, coated pit
Tissue Location: Absorptive epithelia, including renal proximal tubules |
| Uniprot ID |
P98164 |
| Protein Name |
Low-density lipoprotein receptor-related protein 2 |
| Protein Accession # |
NP_004516.2 |
| Gene Symbol |
LRP2 |
| Predicted Species Reactivity |
Human |
| Application |
IHC |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | hepatocarcinoma
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
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