ACE2 Antibody - C-terminal region (OAAB16464)

• Product Number: OAAB16464
• Name: ACE2 Antibody - C-terminal region (OAAB16464)
• Molecular Weight: 92463
• Isotype: Rabbit Ig
• NCBI Gene Id: 59272
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 2 mg/ml
• Gene Full Name: angiotensin converting enzyme 2
• Alias Symbols: ACEH;ACE-related carboxypeptidase;angiotensin I converting enzyme (peptidyl-dipeptidase A) 2;angiotensin I converting enzyme 2;angiotensin-converting enzyme 2;angiotensin-converting enzyme homolog;angiotensin-converting enzyme-related carboxypeptidase;metalloprotease MPROT15;peptidyl-dipeptidase A;truncated angiotensin converting enzyme 2.
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Description of Target: Angiotensin-converting enzyme 2, angiotensin-converting enzyme 2 precursor [Homo sapiens]
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Cellular Location: Processed angiotensin-converting enzyme 2: Secreted
  Tissue Location: Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level) Expressed in heart, kidney, testis, and gastrointestinal system
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
• Immunogen: This ACE2 (SARS Receptor) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 773-805 amino acids from the C-terminal region of human ACE2 (SARS Receptor).
• Uniprot ID: https://www.uniprot.org/uniprot/Q9BYF1
• Protein Name: NP_068576.1, Q9BYF1
• Sample Type Confirmation:

  ACE2 is supported by BioGPS gene expression data to be expressed in K562

• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_068576.1
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Gene Symbol: ACE2
• Predicted Species Reactivity: Human
• Application: Immunohistochemistry-Paraffin, Western blot
• Image 1: Human Testis
  
  Formalin-fixed and paraffin-embedded human testis tissue reacted with ACE2 (SARS Receptor) Antibody (C-term) (Cat.# OAAB16464), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
• Image 2: K562
  
  Western blot analysis of anti-ACE2 C-term Pab (Cat. # OAAB16464) in K562 cell line lysates (35ug/lane). ACE2(arrow) was detected using the purified Pab.
• Image 3: 293
  
  The anti-ACE2 C-term Pab (Cat. # OAAB16464) is used in Western blot to detect ACE2 in 293 cell lysate.

  ACE2 is supported by BioGPS gene expression data to be expressed in K562

• Image 4: breast carcinoma
  
  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.