| Product Number |
OAAB16124 |
| Product Page |
www.avivasysbio.com/stat5a-antibody-phospho-y694-oaab16124.html |
| Name |
STAT5a Antibody (Phospho-Tyr694) (OAAB16124) |
| Molecular Weight |
90647 Da |
| Isotype |
Ig |
| NCBI Gene Id |
6776 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Alias Symbols |
MGF, STAT5 |
| Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Description of Target |
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OAAB16124 |
| Additional Information |
Precautions: Phospho-STAT5a-Y694 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Additional Information |
Function: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation |
| Application Info |
WB: 1:1000
IF: 1:200
IHC-P: 1:50~100 |
| Immunogen |
This STAT5a Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y694 of human STAT5a. |
| Additional Information |
Cellular Location: Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation |
| Uniprot ID |
P42229 |
| Protein Name |
Signal transducer and activator of transcription 5A |
| Protein Accession # |
NP_003143.2 |
| Gene Symbol |
STAT5A |
| Predicted Species Reactivity |
Human |
| Application |
WB, IF, IHC |
| Predicted Homology Based on Immunogen Sequence |
Human |
| Image 1 | human cancer tissue
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
| | Image 2 | HepG2 cell
 | Western blot analysis of anti-Phospho-STAT5 Pab(Cat. #OAAB16124) in HepG2 cell line lysate (35ug/lane). Phospho-STAT5(arrow) was detected using the purified Pab. |
| | Image 3 | an SY5Y cell
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