HTR5A Antibody - N-terminal region (AVARP13047_P050)

Data Sheet
 
Product Number AVARP13047_P050
Product Page www.avivasysbio.com/htr5a-antibody-n-terminal-region-avarp13047-p050.html
Name HTR5A Antibody - N-terminal region (AVARP13047_P050)
Protein Size (# AA) 357 amino acids
Molecular Weight 40kDa
NCBI Gene Id 3361
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
Alias Symbols 5-HT5A
Peptide Sequence Synthetic peptide located within the following region: DLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLV
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Wilkie,M.J., (er) Pharmacogenomics J. (2008) In press
Description of Target The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. HTR5A is a member of 5-hydroxytryptamine (serotonin) receptor family. It is a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1213 BC112021.1 1-1213 1214-1342 AC093726.3 158913-159041 1343-1935 AC092628.3 1996-2588 1936-2400 AK094255.1 2447-2911
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-HTR5A (AVARP13047_P050) antibody
Blocking Peptide For anti-HTR5A (AVARP13047_P050) antibody is Catalog # AAP30720 (Previous Catalog # AAPP01377)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HTR5A
Uniprot ID P47898
Protein Name 5-hydroxytryptamine receptor 5A
Protein Accession # NP_076917
Purification Affinity Purified
Nucleotide Accession # NM_024012
Tested Species Reactivity Human
Gene Symbol HTR5A
Predicted Species Reactivity Human, Guinea Pig
Application WB
Predicted Homology Based on Immunogen Sequence Guinea Pig: 80%; Human: 100%
Image 1
Human Muscle
WB Suggested Anti-HTR5A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Muscle
 

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