Product Number |
AVARP13047_P050 |
Product Page |
www.avivasysbio.com/htr5a-antibody-n-terminal-region-avarp13047-p050.html |
Name |
HTR5A Antibody - N-terminal region (AVARP13047_P050) |
Protein Size (# AA) |
357 amino acids |
Molecular Weight |
40kDa |
NCBI Gene Id |
3361 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
Alias Symbols |
5-HT5A |
Peptide Sequence |
Synthetic peptide located within the following region: DLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLV |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Wilkie,M.J., (er) Pharmacogenomics J. (2008) In press |
Description of Target |
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. HTR5A is a member of 5-hydroxytryptamine (serotonin) receptor family. It is a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1213 BC112021.1 1-1213 1214-1342 AC093726.3 158913-159041 1343-1935 AC092628.3 1996-2588 1936-2400 AK094255.1 2447-2911 |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-HTR5A (AVARP13047_P050) antibody |
Blocking Peptide |
For anti-HTR5A (AVARP13047_P050) antibody is Catalog # AAP30720 (Previous Catalog # AAPP01377) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human HTR5A |
Uniprot ID |
P47898 |
Protein Name |
5-hydroxytryptamine receptor 5A |
Protein Accession # |
NP_076917 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_024012 |
Tested Species Reactivity |
Human |
Gene Symbol |
HTR5A |
Predicted Species Reactivity |
Human, Guinea Pig |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Guinea Pig: 80%; Human: 100% |
Image 1 | Human Muscle
| WB Suggested Anti-HTR5A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Muscle |
|
|