MYOC Antibody - N-terminal region (ARP59771_P050)

• Product Number: ARP59771_P050
• Name: MYOC Antibody - N-terminal region (ARP59771_P050)
• Protein Size (# AA): 344 amino acids
• Molecular Weight: 37kDa
• NCBI Gene Id: 4653
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: myocilin, trabecular meshwork inducible glucocorticoid response
• Alias Symbols: GPOA, JOAG, TIGR, GLC1A, JOAG1
• Peptide Sequence: Synthetic peptide located within the following region: QLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKS
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-MYOC (ARP59771_P050) antibody is Catalog # AAP59771
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human MYOC
• Uniprot ID: Q99972
• Protein Name: myocilin
• Protein Accession #: NP_000252.1
• Purification: Affinity Purified
• Nucleotide Accession #: NM_000261.1
• Tested Species Reactivity: Human
• Gene Symbol: MYOC
• Predicted Species Reactivity: Human, Rat, Guinea Pig
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Guinea Pig: 86%; Human: 100%; Rat: 79%
• Image 1: Human ACHN
  
  Host: Rabbit
  Target Name: MYOC
  Sample Type: ACHN whole cell lysates
  Antibody Dilution: 1.0ug/ml