| Product Number |
ARP58726_P050 |
| Product Page |
www.avivasysbio.com/txndc4-antibody-middle-region-arp58726-p050.html |
| Name |
TXNDC4 Antibody - middle region (ARP58726_P050) |
| Protein Size (# AA) |
406 amino acids |
| Molecular Weight |
45kDa |
| NCBI Gene Id |
23071 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Endoplasmic reticulum protein 44 |
| Alias Symbols |
PDIA10, TXNDC4 |
| Peptide Sequence |
Synthetic peptide located within the following region: LHREFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Mariappan,M., (2008) J. Biol. Chem. 283 (10), 6375-6383 |
| Description of Target |
TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum. |
| Protein Interactions |
FUS; UBC; SUMO1; NEDD8; NUDCD1; UBFD1; OSGEP; LARS; ISOC1; PLD3; PDCD10; FERMT2; YWHAZ; VCL; PFAS; PAK2; G6PD; FHL2; CNN2; TBCB; CKB; env; ELAVL1; SUMO4; RASSF5; USP32; USP46; UIMC1; ERO1LB; ERO1L; ITPR1; CD40; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ERP44 (ARP58726_P050) antibody |
| Blocking Peptide |
For anti-ERP44 (ARP58726_P050) antibody is Catalog # AAP58726 (Previous Catalog # AAPP36422) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human TXNDC4 |
| Uniprot ID |
Q9BS26 |
| Protein Name |
Endoplasmic reticulum resident protein 44 |
| Protein Accession # |
NP_055866 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_015051 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ERP44 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79% |
| Image 1 | Human Placenta
 | WB Suggested Anti-TXNDC4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Placenta |
|
