| Product Number |
ARP58247_P050 |
| Product Page |
www.avivasysbio.com/sumo3-antibody-middle-region-arp58247-p050.html |
| Name |
SUMO3 Antibody - middle region (ARP58247_P050) |
| Protein Size (# AA) |
103 amino acids |
| Molecular Weight |
12kDa |
| NCBI Gene Id |
6612 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) |
| Alias Symbols |
SMT3A, Smt3B, SMT3H1, SUMO-3 |
| Peptide Sequence |
Synthetic peptide located within the following region: MRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVPESSLAGHSF |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Zhang,X.D., (2008) Mol. Cell 29 (6), 729-741 |
| Description of Target |
SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability.SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
PML; USPL1; UBC; HIF1A; ESRRA; EP300; SENP1; USP25; SENP5; SENP2; TP53; SP100; RANGAP1; RGPD8; SUMO3; TRA2B; SDHA; GNB2; GNB1; GART; GAPDH; XRCC6; FLNA; FEN1; FASN; FBL; ENO1; EMD; EIF4A2; EIF4A1; EIF2S1; EEF2; EEF1G; EEF1D; EEF1A1; DNMT1; DYNC1H1; DHX15; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SUMO3 (ARP58247_P050) antibody |
| Blocking Peptide |
For anti-SUMO3 (ARP58247_P050) antibody is Catalog # AAP58247 (Previous Catalog # AAPP32846) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SUMO3 |
| Uniprot ID |
P55854 |
| Protein Name |
Small ubiquitin-related modifier 3 |
| Sample Type Confirmation |
SUMO3 is strongly supported by BioGPS gene expression data to be expressed in MCF7 |
| Protein Accession # |
NP_008867 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006936 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SUMO3 |
| Predicted Species Reactivity |
Human |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Human MCF7
 | WB Suggested Anti-SUMO3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysateSUMO3 is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells |
|
| Image 2 | Human heart
 | Rabbit Anti-SUMO3 Antibody
Catalog Number: ARP58247_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: N/A
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
