| Product Number |
ARP58037_P050 |
| Product Page |
www.avivasysbio.com/nfe2-antibody-middle-region-arp58037-p050.html |
| Name |
NFE2 Antibody - middle region (ARP58037_P050) |
| Protein Size (# AA) |
373 amino acids |
| Molecular Weight |
41kDa |
| NCBI Gene Id |
4778 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Nuclear factor (erythroid-derived 2), 45kDa |
| Alias Symbols |
p45, NF-E2 |
| Peptide Sequence |
Synthetic peptide located within the following region: KPLSLSGLLSEPLQDPLALLDIGLPAGPPKPQEDPESDSGLSLNYSDAES |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
McCormack,M.P., (2006) Blood 108 (7), 2248-2256 |
| Description of Target |
NFE2 is required for activity at the locus control region (LCR) upstream of the globin gene complexes.It requires p18 NF-E2 for binding to the NF-E2 motif. NFE2 may play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron. |
| Protein Interactions |
BTRC; NFE2L3; NFE2L2; NFE2; ATF4; Dlg4; TXN; ITCH; Yap1; Nedd4; WWP1; MAPK8; KAT2B; SCAND1; SSX5; HMGN1; ELF5; PHYHIP; MAFF; MAFG; PEX14; MAFK; CREBBP; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NFE2 (ARP58037_P050) antibody |
| Blocking Peptide |
For anti-NFE2 (ARP58037_P050) antibody is Catalog # AAP58037 (Previous Catalog # AAPP32460) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human NFE2 |
| Uniprot ID |
Q16621 |
| Protein Name |
Transcription factor NF-E2 45 kDa subunit |
| Protein Accession # |
NP_006154 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006163 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
NFE2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 93% |
| Image 1 | Human 293T
 | WB Suggested Anti-NFE2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysate |
|
| Image 2 | Mouse Liver
 | Host: Mouse
Target Name: NFE2
Sample Tissue: Mouse Liver
Antibody Dilution: 1ug/ml |
|
