| Product Number |
ARP54262_P050 |
| Product Page |
www.avivasysbio.com/sqstm1-antibody-middle-region-arp54262-p050.html |
| Name |
SQSTM1 Antibody - middle region (ARP54262_P050) |
| Protein Size (# AA) |
440 amino acids |
| Molecular Weight |
48kDa |
| NCBI Gene Id |
8878 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Sequestosome 1 |
| Alias Symbols |
p60, p62, A170, DMRV, OSIL, PDB3, ZIP3, p62B, NADGP, FTDALS3 |
| Peptide Sequence |
Synthetic peptide located within the following region: EEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Soma,H., (er) Mov. Disord. (2008) In press |
| Description of Target |
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to m |
| Protein Interactions |
HTT; BCL2; ATXN3; MAP1LC3A; tat; GABARAPL1; GABARAPL2; KEAP1; SQSTM1; UBC; TP53; TRIM63; TRIM55; MAP1LC3B; TOLLIP; ULK1; GABARAP; OPTN; SESN2; SUMO3; NBR1; EPAS1; EGLN3; CFTR; DCP2; MGRN1; NEDD8; EDEM1; LGALS3; IKBKG; TNK2; DVL2; FLNB; PSMD12; PSMD10; PSM |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SQSTM1 (ARP54262_P050) antibody |
| Additional Information |
IHC Information: Paraffin embedded pancreas tissue, tested with an antibody dilution of 5 ug/ml. |
| Blocking Peptide |
For anti-SQSTM1 (ARP54262_P050) antibody is Catalog # AAP54262 (Previous Catalog # AAPP31011) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SQSTM1 |
| Uniprot ID |
Q13501 |
| Protein Name |
Sequestosome-1 |
| Protein Accession # |
NP_003891 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003900 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
SQSTM1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93% |
| Image 1 | Human Fetal Liver
 | Host: Rabbit
Target Name: SQSTM1
Sample Type: Human Fetal Liver
Antibody Dilution: 1.0ug/ml |
|
| Image 2 | Human Fetal Lung
 | Host: Rabbit
Target Name: SQSTM1
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml |
|
| Image 3 | Human Fetal Heart
 | Host: Rabbit
Target Name: SQSTM1
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml |
|
| Image 4 | Human Pancreas
 | WB Suggested Anti-SQSTM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Pancreas |
|
| Image 5 | Human Thyroid Gland
 | Rabbit Anti-SQSTM1 Antibody
Catalog Number: ARP54262_P050
Formalin Fixed Paraffin Embedded Tissue: Human Thyroid Gland Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
| Image 6 | Mouse Brain
 | Host: Mouse
Target Name: SQSTM1
Sample Tissue: Mouse Brain
Antibody Dilution: 1ug/ml |
|
| Image 7 | Human Pancreas
 | Pancreas |
|
