| Product Number |
ARP51161_T100 |
| Product Page |
www.avivasysbio.com/cdr2-antibody-n-terminal-region-arp51161-t100.html |
| Name |
CDR2 Antibody - N-terminal region (ARP51161_T100) |
| Protein Size (# AA) |
454 amino acids |
| Molecular Weight |
52 kDa |
| NCBI Gene Id |
1039 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Cerebellar degeneration-related protein 2, 62kDa |
| Alias Symbols |
Yo, CDR62 |
| Peptide Sequence |
Synthetic peptide located within the following region: MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Balbo,M., (2005) FEMS Microbiol. Lett. 249 (2), 359-366 |
| Description of Target |
cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal. |
| Protein Interactions |
SMARCE1; CEP57L1; KANSL1; CCDC153; C4orf46; TXLNA; ALS2CR11; C1orf216; HAUS1; ANKRD36BP1; TCHP; FAM161A; ENKD1; FAM110A; LENG1; SCNM1; SH2D4A; LIN37; RCOR3; TBC1D22B; WDYHV1; CCHCR1; AMOTL2; FZR1; RSPH14; CHIC2; MRPL28; TMCC2; HDAC4; EIF4E2; TTR; COX5B; T |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CDR2 (ARP51161_T100) antibody |
| Additional Information |
IHC Information: Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%. |
| Blocking Peptide |
For anti-CDR2 (ARP51161_T100) antibody is Catalog # AAP51161 (Previous Catalog # AAPP28032) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CDR2 |
| Uniprot ID |
Q01850 |
| Protein Name |
Cerebellar degeneration-related protein 2 |
| Sample Type Confirmation |
CDR2 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_001793 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001802 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CDR2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92% |
| Image 1 | Human Liver
 | Human Liver |
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| Image 2 |
 | 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.
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