CLIC1 Antibody - N-terminal region : HRP (ARP35045_T100-HRP)

Data Sheet
 
Product Number ARP35045_T100-HRP
Product Page www.avivasysbio.com/clic1-antibody-n-terminal-region-hrp-arp35045-t100-hrp.html
Name CLIC1 Antibody - N-terminal region : HRP (ARP35045_T100-HRP)
Protein Size (# AA) 241 amino acids
Molecular Weight 27kDa
Conjugation HRP: Horseradish Peroxidase
NCBI Gene Id 1192
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Chloride intracellular channel 1
Alias Symbols G6, CL1C1, NCC27, CLCNL1
Peptide Sequence Synthetic peptide located within the following region: GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIF
Product Format Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reference Novarino,G., et al., (2004) J. Neurosci. 24 (23), 5322-5330
Description of Target Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
Protein Interactions UBC; PSMD10; SUMO2; SUMO1; NEDD8; FBXO6; ZNF302; NUP62; PRDX4; IKBKG; ZNF184; VCAM1; THRA; RPLP1; NTF4; ITGA4; FN1; ATF2; CPT1A; ATP6V0A1; ATP6V0C; ATP5F1; ALOX5AP; GRK5; MYOC; CDK2; ISG15; ARRB2; SUMO4; LSM1; AKAP9; TRAPPC2;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-CLIC1 (ARP35045_T100-HRP) antibody
Blocking Peptide For anti-CLIC1 (ARP35045_T100-HRP) antibody is Catalog # AAP35045 (Previous Catalog # AAPP06272)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CLIC1
Uniprot ID Q502X1
Protein Name Chloride intracellular channel protein 1
Publications

Yang, J.-Y. et al. Chloride intracellular channel 1 regulates osteoblast differentiation. Bone 45, 1175-85 (2009). WB, Rat, Dog, Horse, Goat, Rabbit, Guinea pig, Human, Mouse, Bovine, Zebrafish 19703605

Protein Accession # NP_001279
Nucleotide Accession # NM_001288
Gene Symbol CLIC1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
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