| Product Number |
ARP34599_P050 |
| Product Page |
www.avivasysbio.com/cbx8-antibody-n-terminal-region-arp34599-p050.html |
| Name |
CBX8 Antibody - N-terminal region (ARP34599_P050) |
| Protein Size (# AA) |
389 amino acids |
| Molecular Weight |
43kDa |
| NCBI Gene Id |
57332 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Chromobox homolog 8 |
| Description |
|
| Alias Symbols |
PC3, RC1 |
| Peptide Sequence |
Synthetic peptide located within the following region: KRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Dietrich,N., (2007) EMBO J. 26 (6), 1637-1648 |
| Description of Target |
CBX8 is one of the proteins homolog to the Polycomb group (PcG) proteins. They assemble to form large multiprotein complexes involved in gene silencing. Evidence suggests that PcG complexes are heterogeneous with respect to both protein composition and specific function. |
| Protein Interactions |
CCDC57; KRT40; FSD2; GPRASP2; LZTS2; TSGA10; HMBOX1; CCDC136; RPGRIP1; KCTD9; MTUS2; MID2; PNMA2; IKZF1; CALCOCO2; ZBTB14; TRAF2; TFCP2; SOX5; RING1; KIFC3; GOLGA2; PHC2; UBC; EED; RNF2; BMI1; SUZ12; MLLT1; LOC100131689; ZNF717; CHAMP1; HIST1H2BA; UBR1; E |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CBX8 (ARP34599_P050) antibody |
| Blocking Peptide |
For anti-CBX8 (ARP34599_P050) antibody is Catalog # AAP34599 (Previous Catalog # AAPP05781) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CBX8 |
| Uniprot ID |
Q9HC52 |
| Protein Name |
Chromobox protein homolog 8 |
| Publications |
Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis. Cell Rep. 26, 3643-3656.e7 (2019). 30917318 |
| Protein Accession # |
NP_065700 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_020649 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CBX8 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 86% |
| Image 1 | Human COLO205
 | WB Suggested Anti-CBX8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: COLO205 cell lysate |
|
