| Product Number |
ARP34309_T100 |
| Product Page |
www.avivasysbio.com/sertad1-antibody-n-terminal-region-arp34309-t100.html |
| Name |
SERTAD1 Antibody - N-terminal region (ARP34309_T100) |
| Protein Size (# AA) |
236 amino acids |
| Molecular Weight |
25kDa |
| NCBI Gene Id |
29950 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
SERTA domain containing 1 |
| Description |
|
| Alias Symbols |
SEI1, TRIPBR1, TRIP-Br1 |
| Peptide Sequence |
Synthetic peptide located within the following region: MLSKGLKRKREEEEEKEPLAVDSWWLDPGHTAVAQAPPAVASSSLFDLSV |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Li,J., (2005) Biochemistry 44 (40), 13246-13256 |
| Description of Target |
SERTA is a transcriptional regulator that interacts with the PHD-bromodomain of co-repressors of Kruppel-associated box (KRAB)-mediated repression, KRIP-1(TIF1beta) and TIF1alpha, as well as the co-activator/adaptor p300/CBP. It is a component of a multiprotein complex containing E2F-1 and DP-1. |
| Protein Interactions |
FAH; P4HA3; PATE1; CIB3; EGLN3; ZNF410; ROPN1; SFI1; MVP; PPP2R1A; POT1; ASB8; SETD7; RCHY1; SPEN; RBX1; TLR4; TGM2; STAT5B; SMAD3; HSPB1; HIVEP1; EP300; COPB1; ATXN7L3; UBC; PRDM4; DENND4A; TCEB1; CHURC1; TRIM28; SUPT7L; KAT2B; KLHL42; CDKN2A; CREBBP; CD |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SERTAD1 (ARP34309_T100) antibody |
| Blocking Peptide |
For anti-SERTAD1 (ARP34309_T100) antibody is Catalog # AAP34309 (Previous Catalog # AAPP05659) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SERTAD1 |
| Uniprot ID |
Q9UHV2 |
| Protein Name |
SERTA domain-containing protein 1 |
| Publications |
Sertad1 Induces Neurological Injury after Ischemic Stroke via the CDK4/p-Rb Pathway. Mol Cells. (2022). 35014620 |
| Protein Accession # |
NP_037508 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_013376 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SERTAD1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 90%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%; Yeast: 91% |
| Image 1 | Human Muscle
 | Human Muscle |
|
| Image 2 | Human Placenta
 | WB Suggested Anti-SERTAD1 Antibody Titration: 0.125ug/ml
ELISA Titer: 1:312500
Positive Control: Human Placenta |
|
