Product Number |
ARP34151_T100 |
Product Page |
www.avivasysbio.com/atf2-antibody-c-terminal-region-arp34151-t100.html |
Name |
ATF2 Antibody - C-terminal region (ARP34151_T100) |
Protein Size (# AA) |
505 amino acids |
Molecular Weight |
55kDa |
NCBI Gene Id |
1386 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Activating transcription factor 2 |
Alias Symbols |
HB16, CREB2, TREB7, CREB-2, CRE-BP1 |
Peptide Sequence |
Synthetic peptide located within the following region: LRNEVAQLKQLLLAHKDCPVTAMQKKSGYHTADKDDSSEDISVPSSPHTE |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Kravets,A., et al., (2004) J. Biol. Chem. 279 (19), 19916-19923 |
Description of Target |
ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. |
Protein Interactions |
MAPK10; MAPK9; MAPK8; MAPK1; SUMO1; KIFC3; FOS; MAPK14; EXOSC8; JUN; CREBBP; ATF2; CEBPG; BACH1; ATF4; ATF3; BATF3; DDIT3; BATF; FOSL1; H2AFY; RB1; GAPDH; NME2P1; TUBB; SFXN1; RAB2B; TMX1; GRPEL1; COLGALT1; AHNAK; SQRDL; RTN4; APMAP; C19orf10; RAB14; ERO1 |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ATF2 (ARP34151_T100) antibody |
Blocking Peptide |
For anti-ATF2 (ARP34151_T100) antibody is Catalog # AAP34151 (Previous Catalog # AAPP05413) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human ATF2 |
Uniprot ID |
P15336-2 |
Protein Name |
Cyclic AMP-dependent transcription factor ATF-2 |
Protein Accession # |
NP_001871 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001880 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
ATF2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Mouse Testis
| Host: Mouse Target Name: ATF2 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml |
|
Image 2 | Human Jurkat
| WB Suggested Anti-ATF2 Antibody Titration: 1.25ug/ml Positive Control: Jurkat cell lysate |
|
Image 3 | Human kidney
| Human kidney |
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Image 4 | Human Intestine
| Human Intestine |
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Image 5 | Human Ovary
| Rabbit Anti-ATF2 Antibody Catalog Number: ARP34151_T100 Formalin Fixed Paraffin Embedded Tissue: Human Ovary Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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