APOBEC3G Antibody - N-terminal region : FITC (ARP33540_T100-FITC)

Data Sheet
 
Product Number ARP33540_T100-FITC
Product Page www.avivasysbio.com/apobec3g-antibody-n-terminal-region-fitc-arp33540-t100-fitc.html
Name APOBEC3G Antibody - N-terminal region : FITC (ARP33540_T100-FITC)
Protein Size (# AA) 384 amino acids
Molecular Weight 46kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 60489
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
Alias Symbols A3G, ARCD, ARP9, ARP-9, CEM15, CEM-15, MDS019, bK150C2.7, dJ494G10.1
Peptide Sequence Synthetic peptide located within the following region: AKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKC
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Reference Rose,K.M., et al., (2004) J. Biol. Chem. 279 (40), 41744-41749
Description of Target Anti-APOBEC3G is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
Protein Interactions vpr; vif; UNG1; APP; UBC; CBFB; APOBEC3G; HSPA4; gag; PTN; PRKACA; UBA52;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-APOBEC3G (ARP33540_T100-FITC) antibody
Blocking Peptide For anti-APOBEC3G (ARP33540_T100-FITC) antibody is Catalog # AAP33540
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human APOBEC3G
Uniprot ID Q9HC16
Protein Name DNA dC->dU-editing enzyme APOBEC-3G
Publications

Chen, H., Wang, L.-W., Huang, Y.-Q. & Gong, Z.-J. Interferon-alpha Induces High Expression of APOBEC3G and STAT-1 in Vitro and in Vivo. Int. J. Mol. Sci. 11, 3501-12 (2010). WB, Human, Pig 20957108

Sample Type Confirmation

APOBEC3G is strongly supported by BioGPS gene expression data to be expressed in Daudi

Protein Accession # NP_068594
Nucleotide Accession # NM_021822
Gene Symbol APOBEC3G
Predicted Species Reactivity Human, Pig
Application WB
Predicted Homology Based on Immunogen Sequence Human: 100%; Pig: 79%
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