ACSL1 Antibody - C-terminal region : Biotin (ARP32784_P050-Biotin)

Data Sheet
 
Product Number ARP32784_P050-Biotin
Product Page www.avivasysbio.com/acsl1-antibody-c-terminal-region-biotin-arp32784-p050-biotin.html
Name ACSL1 Antibody - C-terminal region : Biotin (ARP32784_P050-Biotin)
Protein Size (# AA) 698 amino acids
Molecular Weight 78kDa
Conjugation Biotin
NCBI Gene Id 2180
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Acyl-CoA synthetase long-chain family member 1
Alias Symbols ACS1, LACS, FACL1, FACL2, LACS1, LACS2
Peptide Sequence Synthetic peptide located within the following region: GSFEELCRNKDVKKAILEDMVRLGKDSGLKPFEQVKGITLHPELFSIDNG
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Reference Ghosh,B., et al., (1995) Mol. Cell. Biochem. 151 (1), 77-81
Description of Target ACSL1 encodes an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions SUMO2; PARK2; ATP4A; UBC; NR3C2; ECT2; UBD;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-ACSL1 (ARP32784_P050-Biotin) antibody
Additional Information IHC Information: Paraffin embedded placenta tissue, tested with an antibody dilution of 5 ug/ml.
Blocking Peptide For anti-ACSL1 (ARP32784_P050-Biotin) antibody is Catalog # AAP32784 (Previous Catalog # AAPP03803)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ACSL1
Uniprot ID P33121
Protein Name Long-chain-fatty-acid--CoA ligase 1
Publications

Golej, D. L. et al. Long-chain acyl-CoA synthetase 4 modulates prostaglandin E? release from human arterial smooth muscle cells. J. Lipid Res. 52, 782-93 (2011). WB, Human, Mouse, Rat, Dog, Bovine, Horse, Zebrafish, Guinea pig 21242590

Sample Type Confirmation

ACSL1 is strongly supported by BioGPS gene expression data to be expressed in 721_B

Protein Accession # NP_001986
Purification Affinity Purified
Nucleotide Accession # NM_001995
Gene Symbol ACSL1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Guinea Pig: 79%; Horse: 85%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%
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