Product Number |
ARP31121_P050 |
Product Page |
www.avivasysbio.com/rbpsuh-antibody-c-terminal-region-arp31121-p050.html |
Name |
RBPSUH Antibody - C-terminal region (ARP31121_P050) |
Protein Size (# AA) |
485 amino acids |
Molecular Weight |
56kDa |
NCBI Gene Id |
3516 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Recombination signal binding protein for immunoglobulin kappa J region |
Alias Symbols |
SUH, csl, AOS3, CBF1, KBF2, CBF-1, RBP-J, RBPJK, IGKJRB, RBP-JK, RBPSUH, IGKJRB1, RBP-J kappa |
Peptide Sequence |
Synthetic peptide located within the following region: RPHCSAAGAILRANSSQVPPNESNTNSEGSYTNASTNSTSVTSSTATVVS |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
MacKenzie, F., et al., (2004) Blood 104 (6), 1760-1768 |
Description of Target |
RBPSUH is a DNA binding protein that activates a full transcriptional response but only demonstrates partial anti-apoptotic activity. RTA-mediated redirection of RBPSUH activity from repression to activation is critical for lytic viral replication. |
Protein Interactions |
Notch1; MAML1; MED27; MYC; FHL1; CAMK4; PHF8; KDM1A; SMARCA4; APP; ORF50; UBB; HHV8GK18_gp81; BCL6B; KAT5; ELAVL1; SPEN; RUNX1T1; RUNX3; RPS6KA6; GSK3B; GADD45A; KDM5A; H; lid; KAT2B; SUFU; CIR1; SNW1; SND1; HDAC1; NCOR1; NCOR2; NOTCH3; NOTCH2; NOTCH4; HM |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-RBPJ (ARP31121_P050) antibody |
Blocking Peptide |
For anti-RBPJ (ARP31121_P050) antibody is Catalog # AAP31121 (Previous Catalog # AAPS18703) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human RBPSUH |
Uniprot ID |
Q06330 |
Protein Name |
Recombining binding protein suppressor of hairless |
Protein Accession # |
NP_976028 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_203283 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
RBPJ |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
IHC, IP, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100% |
Image 1 | Human HepG2
| WB Suggested Anti-RBPSUH Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate |
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Image 2 | Human K562
| K562 |
|
Image 3 | Human Stomach
| Human Stomach |
|
Image 4 | Human Liver
| Human Liver |
|
Image 5 | Mouse Liver
| Host: Mouse Target Name: RBPJ Sample Tissue: Mouse Liver Antibody Dilution: 1ug/ml |
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