Product Number |
ARP30622_P050 |
Product Page |
www.avivasysbio.com/tnfrsf10a-antibody-c-terminal-region-arp30622-p050.html |
Name |
TNFRSF10A Antibody - C-terminal region (ARP30622_P050) |
Protein Size (# AA) |
468 amino acids |
Molecular Weight |
50kDa |
NCBI Gene Id |
8797 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Tumor necrosis factor receptor superfamily, member 10a |
Alias Symbols |
DR4, APO2, CD261, TRAILR1, TRAILR-1 |
Peptide Sequence |
Synthetic peptide located within the following region: RAGTAGPGDALYAMLMKWVNKTGRNASIHTLLDALERMEERHAKEKIQDL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. |
Protein Interactions |
UBC; MARCH8; MARCH1; CFLAR; FADD; CUL3; TRAF2; CASP8; SQSTM1; TNFRSF10B; CBL; MOAP1; RASSF1; TNFRSF10D; TNFRSF10A; TNFSF10; MADD; BCL10; TRADD; RIPK1; DAP3; BTK; CD4; COL2A1; CASP10; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-TNFRSF10A (ARP30622_P050) antibody |
Blocking Peptide |
For anti-TNFRSF10A (ARP30622_P050) antibody is Catalog # AAP30622 |
Uniprot ID |
O00220 |
Protein Name |
Tumor necrosis factor receptor superfamily member 10A |
Protein Accession # |
NP_003835 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_003844 |
Tested Species Reactivity |
Human |
Gene Symbol |
TNFRSF10A |
Predicted Species Reactivity |
Human, Mouse |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Human: 100%; Mouse: 80% |
Image 1 | Human ACHN
| WB Suggested Anti-TNFRSF10A Antibody Titration: 1.0 ug/ml Positive Control: ACHN Whole Cell |
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