| Product Number |
P100892_P050 |
| Product Page |
www.avivasysbio.com/gtf2e1-antibody-c-terminal-region-p100892-p050.html |
| Name |
GTF2E1 Antibody - C-terminal region (P100892_P050) |
| Protein Size (# AA) |
439 amino acids |
| Molecular Weight |
49kDa |
| Subunit |
1 |
| NCBI Gene Id |
2960 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
General transcription factor IIE, polypeptide 1, alpha 56kDa |
| Description |
|
| Alias Symbols |
FE, TF2E1, TFIIE-A |
| Peptide Sequence |
Synthetic peptide located within the following region: VADDPIVMVAGRPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ohkuma,Y., et al., (1991) Nature 354 (6352), 398-401 |
| Description of Target |
The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57,000 (TFIIE-alpha) and 34,000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation |
| Protein Interactions |
UBC; AARSD1; ACBD3; XPO5; SH3GLB2; OXR1; NSUN2; RPUSD2; SNF8; EFTUD2; TTC1; SH3GL1; SARS; HARS; SRPK2; TCEA1; GTF2H1; GTF2E2; CDK7; APP; tat; GTF2F1; ELAVL1; ZSCAN1; ZBTB9; TRIM15; PCBD2; TRIM29; CBFA2T2; IKBKG; ATF7IP; TAF6; GTF2B; TRIM24; SND1; GTF2H4; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-GTF2E1 (P100892_P050) antibody |
| Blocking Peptide |
For anti-GTF2E1 (P100892_P050) antibody is Catalog # AAP31240 (Previous Catalog # AAPP01985) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2E1 |
| Uniprot ID |
P29083 |
| Protein Name |
General transcription factor IIE subunit 1 |
| Protein Accession # |
NP_005504 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005513 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
GTF2E1 |
| Predicted Species Reactivity |
Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Daudi
 | WB Suggested Anti-GTF2E1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Daudi cell lysate |
|
| Image 2 | Human Muscle
 | Human Muscle |
|
