| Product Number |
ARP50535_P050 |
| Product Page |
www.avivasysbio.com/cog5-antibody-n-terminal-region-arp50535-p050.html |
| Name |
COG5 Antibody - N-terminal region (ARP50535_P050) |
| Protein Size (# AA) |
860 amino acids |
| Molecular Weight |
95kDa |
| Subunit |
5 |
| NCBI Gene Id |
10466 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Component of oligomeric golgi complex 5 |
| Alias Symbols |
CDG2I, GTC90, GOLTC1 |
| Peptide Sequence |
Synthetic peptide located within the following region: MGWVGGRRRDSASPPGRSRSAADDINPAPANMEGGGGSVAVAGLGARGSG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Oka,T., (2005) J. Biol. Chem. 280 (38), 32736-32745 |
| Description of Target |
COG5 is required for normal Golgi function.Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG5 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM]. |
| Protein Interactions |
UBC; COG7; EGFR; VCP; COG8; COG3; COG6; COG4; COG2; COG1; TRAF5; Poc1b; Nek9; RAC1; APC; MEFV; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-COG5 (ARP50535_P050) antibody |
| Blocking Peptide |
For anti-COG5 (ARP50535_P050) antibody is Catalog # AAP50535 (Previous Catalog # AAPY02421) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human COG5 |
| Uniprot ID |
Q9UP83-2 |
| Protein Name |
Conserved oligomeric Golgi complex subunit 5 |
| Protein Accession # |
NP_006339 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006348 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
COG5 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Human THP1
 | WB Suggested Anti-COG5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: THP-1 cell lysate |
| | Image 2 | Human, Mouse
 | Sample Type: 1. Human Cervical Cancer Cell Lysate (15ug)
2. Monkey Fibroblast Cell Lysate (15ug)
3. Human Cervical Cancer Cell transfected with Myc-COG4 (15ug)
Primary Dilution: 1:1000
Secondary Antibody: goat anti-Rabbit
Secondary Dilution: 1:40,000
Image Submitted by: Dr. Jakob Szwedo, Dr. Lupashin's Lab
University of Arkansas for Medical SciencesSee Customer Feedback tab for detailed information.
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