| Product Number |
ARP48001_T100 |
| Product Page |
www.avivasysbio.com/nr2c2-antibody-c-terminal-region-arp48001-t100.html |
| Name |
NR2C2 Antibody - C-terminal region (ARP48001_T100) |
| Protein Size (# AA) |
615 amino acids |
| Molecular Weight |
67kDa |
| NCBI Gene Id |
7182 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Nuclear receptor subfamily 2, group C, member 2 |
| Alias Symbols |
TR4, TAK1 |
| Peptide Sequence |
Synthetic peptide located within the following region: AQCAQVMSLSTILAAIVNHLQNSIQEDKLSGDRIKQVMEHIWKLQEFCNS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lin,W.J., (2003) J. Biol. Chem. 278 (11), 9353-9360 |
| Description of Target |
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes.Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996).[supplied by OMIM]. |
| Protein Interactions |
VPRBP; CUL4B; UBC; DDB1; KDM1A; NR2C2; HSP90AA1; JAZF1; TAB2; TRAF6; PELI1; PELI2; RBCK1; PDLIM7; TAB1; TRIM28; MTA1; HDAC3; NR2C1; RBBP4; HDAC1; DNMT1; CHD4; Cebpb; ITSN2; CD2AP; RXRB; NR2C2AP; PEBP1; HSP90AB1; CDC37; IKBKB; FKBP5; TRAF2; CHUK; HNF4A; AR |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NR2C2 (ARP48001_T100) antibody |
| Additional Information |
IHC Information: HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%. |
| Blocking Peptide |
For anti-NR2C2 (ARP48001_T100) antibody is Catalog # AAP48001 (Previous Catalog # AAPS20504) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human NR2C2 |
| Uniprot ID |
P49116 |
| Protein Name |
Nuclear receptor subfamily 2 group C member 2 |
| Protein Accession # |
NP_003289 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_003298 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NR2C2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Skin
 | Human Skin |
|
| Image 2 | Human HepG2
 | NR2C2 antibody - C-terminal region (ARP48001_T100) validated by WB using HepG2 cell lysate at 2.5ug/ml. |
|
