| Product Number |
ARP45623_T100 |
| Product Page |
www.avivasysbio.com/nr1i3-antibody-n-terminal-region-arp45623-t100.html |
| Name |
NR1I3 Antibody - N-terminal region (ARP45623_T100) |
| Protein Size (# AA) |
348 amino acids |
| Molecular Weight |
39kDa |
| NCBI Gene Id |
9970 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Nuclear receptor subfamily 1, group I, member 3 |
| Alias Symbols |
CAR, CAR1, MB67 |
| Peptide Sequence |
Synthetic peptide located within the following region: MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ferguson,S.S., (2005) Mol. Pharmacol. 68 (3), 747-757 |
| Description of Target |
NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses. |
| Protein Interactions |
HSP90AA1; RXRA; CHD9; SNX13; SNRPD3; IGH; PSMC5; PSMC4; EIF3I; SRC; MAP4; FTH1; HNF4A; NR0B2; PPARGC1A; MED1; NCOA1; POU1F1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NR1I3 (ARP45623_T100) antibody |
| Blocking Peptide |
For anti-NR1I3 (ARP45623_T100) antibody is Catalog # AAP45623 (Previous Catalog # AAPP11906) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I3 |
| Uniprot ID |
Q5VTW5 |
| Protein Name |
Nuclear receptor subfamily 1 group I member 3 |
| Protein Accession # |
NP_005113 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_005122 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NR1I3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 90%; Dog: 92%; Guinea Pig: 79%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92% |
| Image 1 | Human Liver
 | Human Liver |
|
| Image 2 | Human Liver
 | WB Suggested Anti-NR1I3 Antibody Titration: 1.25ug/ml
Positive Control: Human Liver |
|
| Image 3 | Human liver, Human stomach
 | Host: Rabbit
Target: NR1I3
Positive control (+): Human liver (LI)
Negative control (-): Human stomach (ST)
Antibody concentration: 5ug/ml |
|
