| Product Number |
ARP43517_T100 |
| Product Page |
www.avivasysbio.com/got2-antibody-n-terminal-region-arp43517-t100.html |
| Name |
GOT2 Antibody - N-terminal region (ARP43517_T100) |
| Protein Size (# AA) |
430 amino acids |
| Molecular Weight |
45kDa |
| NCBI Gene Id |
2806 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) |
| Description |
|
| Alias Symbols |
KAT4, DEE82, KATIV, KYAT4, mitAAT |
| Peptide Sequence |
Synthetic peptide located within the following region: PPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Suzuki,Y., Gene 200 (1-2), 149-156 (1997) |
| Description of Target |
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. |
| Protein Interactions |
FUS; UBC; NEDD8; MDM2; CDK2; CCL21; GLRX; GAPDH; APCS; AI837181; HDAC5; PSMD4; THOC7; ZDHHC6; GLUD1; HSPA8; PC; MDH2; CTNNBIP1; MPG; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-GOT2 (ARP43517_T100) antibody |
| Blocking Peptide |
For anti-GOT2 (ARP43517_T100) antibody is Catalog # AAP43517 (Previous Catalog # AAPS15710) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human GOT2 |
| Uniprot ID |
P00505 |
| Protein Name |
Aspartate aminotransferase, mitochondrial |
| Publications |
Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation. PLoS One. 8, e64093 (2013). 23704975 |
| Protein Accession # |
NP_002071 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_002080 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
GOT2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100% |
| Image 1 | Human 293T
 | WB Suggested Anti-GOT2 Antibody Titration: 1.0ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysate |
|
