| Product Number |
ARP43088_P050 |
| Product Page |
www.avivasysbio.com/wwp2-antibody-middle-region-arp43088-p050.html |
| Name |
WWP2 Antibody - middle region (ARP43088_P050) |
| Protein Size (# AA) |
431 amino acids |
| Molecular Weight |
47kDa |
| NCBI Gene Id |
11060 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
WW domain containing E3 ubiquitin protein ligase 2 |
| Alias Symbols |
AIP2, WWp2-like |
| Peptide Sequence |
Synthetic peptide located within the following region: EMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYDRSFRWKYH |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Rougier,J.S., Am. J. Physiol., Cell Physiol. 288 (3), C692-C701 (2005) |
| Description of Target |
WWP2 is a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. WWP2 contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions.This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Protein Interactions |
LGALS9B; ANKRD44; FBXL18; VPS37C; PABPC1; RUSC1; HNRNPUL1; WWP2; PAIP1; TRAF4; FAM189A2; PDLIM7; EIF3A; WIPF1; UBE2L3; UBC; SNRPC; PTCH1; SMAD6; SMAD3; EZH2; PTEN; UBE2D3; FBXL15; RNF11; ARRDC1; ARRDC4; ARRDC3; VPS11; UBE2G1; UBE2J2; UBE2E3; UBE2E1; UBE2D |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-WWP2 (ARP43088_P050) antibody |
| Blocking Peptide |
For anti-WWP2 (ARP43088_P050) antibody is Catalog # AAP43088 (Previous Catalog # AAPP25063) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human WWP2 |
| Uniprot ID |
O00308 |
| Protein Name |
NEDD4-like E3 ubiquitin-protein ligase WWP2 |
| Sample Type Confirmation |
WWP2 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_955456 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_199424 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
WWP2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%; Sheep: 100%; Zebrafish: 80% |
| Image 1 | Human Lung
 | Rabbit Anti-WWP2 Antibody
Catalog Number: ARP43088
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Human kidney
 | Human kidney |
|
| Image 3 | Human Fetal Lung
 | Host: Rabbit
Target Name: WWP2
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml |
|
