| Product Number |
ARP42995_T100 |
| Product Page |
www.avivasysbio.com/amfr-antibody-c-terminal-region-arp42995-t100.html |
| Name |
AMFR Antibody - C-terminal region (ARP42995_T100) |
| Protein Size (# AA) |
643 amino acids |
| Molecular Weight |
73kDa |
| NCBI Gene Id |
267 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Autocrine motility factor receptor, E3 ubiquitin protein ligase |
| Alias Symbols |
GP78, RNF45 |
| Peptide Sequence |
Synthetic peptide located within the following region: FGEVEVEPSEVEDFEARGSRFSKSADERQRMLVQRKDELLQQARKRFLNK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lehner,B. (2004) Genome Res. 14 (7), 1315-1323 |
| Description of Target |
Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000).[supplied by OMIM]. |
| Protein Interactions |
VCP; UBE2G1; HSPA5; ERLIN2; INSIG1; HMGCR; DHFR; AMFR; UBE2D1; UBC; GPI; TRIM25; DGAT2; UBE2K; Ube2g2; NPLOC4; HERPUD1; BAG6; MAVS; YOD1; ADRA1D; DERL2; ADRB2; FAF2; SEC61B; RPN1; STT3A; STT3B; AUP1; MDC1; SNED1; DDOST; GET4; UBXN4; UBL4A; CD82; SARAF; IT |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-AMFR (ARP42995_T100) antibody |
| Blocking Peptide |
For anti-AMFR (ARP42995_T100) antibody is Catalog # AAP43141 (Previous Catalog # AAPP11301) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human AMFR |
| Uniprot ID |
Q9UKV5 |
| Protein Name |
AMFR protein EMBL AAH56869.1 |
| Sample Type Confirmation |
AMFR is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
AAH56869 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_013446 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
AMFR |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human HepG2
 | WB Suggested Anti-AMFR Antibody Titration: 2.5ug/ml
Positive Control: HepG2 cell lysateAMFR is supported by BioGPS gene expression data to be expressed in HepG2 |
|
| Image 2 | Human MDA-MB-435s Whole Cell
 | Host: Rabbit
Target Name: AMFR
Sample Tissue: Human MDA-MB-435s Whole Cell
Antibody Dilution: 1ug/ml |
|
| Image 3 | Human HepG2 Whole Cell
 | Host: Rabbit
Target Name: AMFR
Sample Tissue: Human HepG2 Whole Cell
Antibody Dilution: 1ug/ml |
|
