PBEF1 Antibody - C-terminal region (ARP42254_T100)

Data Sheet
 
Product Number ARP42254_T100
Product Page www.avivasysbio.com/pbef1-antibody-c-terminal-region-arp42254-t100.html
Name PBEF1 Antibody - C-terminal region (ARP42254_T100)
Protein Size (# AA) 491 amino acids
Molecular Weight 54kDa
NCBI Gene Id 10135
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Nicotinamide phosphoribosyltransferase
Alias Symbols VF, PBEF, PBEF1, VISFATIN, 1110035O14Rik
Peptide Sequence Synthetic peptide located within the following region: CSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Chen,M.P., (2006) J. Clin. Endocrinol. Metab. 91 (1), 295-299
Description of Target PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Protein Interactions UBC; NEDD8; NDRG1; CTSA; PEPD; MVD; GSR; ASS1; ANXA6; CD81; AKT2; ADORA2A; IFITM3; ND1; GGT1; FTL; CUL5; DDA1; GBAS; FANCA;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-NAMPT (ARP42254_T100) antibody
Blocking Peptide For anti-NAMPT (ARP42254_T100) antibody is Catalog # AAP42254 (Previous Catalog # AAPP24675)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human PBEF1
Uniprot ID P43490
Protein Name Nicotinamide phosphoribosyltransferase
Protein Accession # NP_005737
Purification Protein A purified
Nucleotide Accession # NM_005746
Tested Species Reactivity Human
Gene Symbol NAMPT
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human Jurkat
WB Suggested Anti-PBEF1 Antibody Titration: 2.5ug/ml
Positive Control: Jurkat cell lysate
 

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