| Product Number |
ARP42118_T100 |
| Product Page |
www.avivasysbio.com/tnni1-antibody-middle-region-arp42118-t100.html |
| Name |
TNNI1 Antibody - middle region (ARP42118_T100) |
| Protein Size (# AA) |
187 amino acids |
| Molecular Weight |
21kDa |
| NCBI Gene Id |
7135 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Troponin I type 1 (skeletal, slow) |
| Alias Symbols |
TNN1, SSTNI |
| Peptide Sequence |
Synthetic peptide located within the following region: PPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ralli,S., (2005) Am. Heart J. 150 (6), 1220-1227 |
| Description of Target |
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Each troponin-tropomyosin complex contains 1 molecule from each of the 3 troponins: T, C, and I. The troponin I (TNI) subfamily contains three genes: TNI-skeletal-fast-twitch, TNI-skeletal-slow-twitch, and TNI-cardiac. TNNI1 prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. |
| Protein Interactions |
PNMA1; MDFI; TRIM63; TRIM55; TNNC1; TNNT2; EIF3I; CCDC85B; TNNT1; ACTA1; PKD2L1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TNNI1 (ARP42118_T100) antibody |
| Blocking Peptide |
For anti-TNNI1 (ARP42118_T100) antibody is Catalog # AAP42118 (Previous Catalog # AAPS12101) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human TNNI1 |
| Uniprot ID |
P19237 |
| Protein Name |
Troponin I, slow skeletal muscle |
| Protein Accession # |
NP_003272 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_003281 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TNNI1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-TNNI1 Antibody Titration: 2.5ug/ml
Positive Control: Jurkat cell lysate |
|
