| Product Number |
ARP40741_P050 |
| Product Page |
www.avivasysbio.com/cpsf1-antibody-middle-region-arp40741-p050.html |
| Name |
CPSF1 Antibody - middle region (ARP40741_P050) |
| Protein Size (# AA) |
1443 amino acids |
| Molecular Weight |
161kDa |
| Subunit |
1 |
| NCBI Gene Id |
29894 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Cleavage and polyadenylation specific factor 1, 160kDa |
| Alias Symbols |
MYP27, CPSF160, P/cl.18, HSU37012 |
| Peptide Sequence |
Synthetic peptide located within the following region: GCYDMWTVIAPVRKEEEDNPKGEGTEQEPSTTPEADDDGRRHGFLILSRE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 |
| Description of Target |
CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. |
| Protein Interactions |
REL; RBBP6; UBC; STAU1; LGR4; WWOX; RPA3; RPA2; RPA1; EED; EZH2; NEDD4; TARDBP; ICK; CLK2; HDAC6; NPM1; IL7R; HMOX1; TUT1; FIP1L1; RNPC3; WDR33; CPSF2; MED8; CPSF3; GTF3C3; POLR2A; COPS6; CUL3; SIRT7; SMARCAD1; CSTF2T; PAPOLA; CSTF3; GLIS2; RRAGA; TBP; TA |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CPSF1 (ARP40741_P050) antibody |
| Blocking Peptide |
For anti-CPSF1 (ARP40741_P050) antibody is Catalog # AAP40741 (Previous Catalog # AAPY00993) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human CPSF1 |
| Uniprot ID |
Q10570 |
| Protein Name |
Cleavage and polyadenylation specificity factor subunit 1 |
| Protein Accession # |
NP_037423 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_013291 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CPSF1 |
| Predicted Species Reactivity |
Human, Rat, Horse |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Horse: 79%; Human: 100%; Rat: 77% |
| Image 1 | Human HCT116 Whole Cell
 | Host: Rabbit
Target Name: CPSF1
Sample Tissue: Human HCT116 Whole Cell
Antibody Dilution: 1ug/ml |
|
| Image 2 | Transfected 293T
 | WB Suggested Anti-CPSF1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T |
|
