Product Number |
ARP40640_T100 |
Product Page |
www.avivasysbio.com/syncrip-antibody-n-terminal-region-arp40640-t100.html |
Name |
SYNCRIP Antibody - N-terminal region (ARP40640_T100) |
Protein Size (# AA) |
623 amino acids |
Molecular Weight |
69kDa |
NCBI Gene Id |
10492 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Synaptotagmin binding, cytoplasmic RNA interacting protein |
Alias Symbols |
PP68, NSAP1, GRYRBP, HNRNPQ, HNRPQ1, GRY-RBP, hnRNP-Q |
Peptide Sequence |
Synthetic peptide located within the following region: MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAG |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Bannai,H., (2004) J. Biol. Chem. 279 (51), 53427-53434 |
Description of Target |
Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. SYNCRIP may be involved in translationally coupled mRNA turnover. It implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. It interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. |
Protein Interactions |
FUS; PRMT8; UBC; SPRTN; SUMO2; SUMO3; STAU1; MDM2; RPA3; RPA2; RPA1; RNF2; EED; rev; GNB2L1; IQGAP1; RPS21; RPL24; RPL23A; PSMD7; RPSA; IARS; PRMT1; HNRNPU; FKBP3; MAP1S; C14orf166; RPS27L; NELFB; PARK2; FBXO6; TARDBP; CSF2; CD81; IGSF8; HMGA2; ICAM1; HMG |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SYNCRIP (ARP40640_T100) antibody |
Blocking Peptide |
For anti-SYNCRIP (ARP40640_T100) antibody is Catalog # AAP40640 (Previous Catalog # AAPP10620) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SYNCRIP |
Uniprot ID |
O60506 |
Protein Name |
Heterogeneous nuclear ribonucleoprotein Q |
Protein Accession # |
NP_006363 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_006372 |
Tested Species Reactivity |
Human |
Gene Symbol |
SYNCRIP |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human HepG2
| WB Suggested Anti-SYNCRIP Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysate |
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