| Product Number |
ARP40528_T100 |
| Product Page |
www.avivasysbio.com/sfrs10-antibody-n-terminal-region-arp40528-t100.html |
| Name |
SFRS10 Antibody - N-terminal region (ARP40528_T100) |
| Protein Size (# AA) |
288 amino acids |
| Molecular Weight |
32kDa |
| NCBI Gene Id |
6434 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Transformer 2 beta homolog (Drosophila) |
| Alias Symbols |
SFRS10, SRFS10, TRAN2B, PPP1R156, TRA2-BETA, Htra2-beta |
| Peptide Sequence |
Synthetic peptide located within the following region: MSDSGEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Helmken,C., (2003) Hum. Genet. 114 (1), 11-21 |
| Description of Target |
SFRS10 contains 1 RRM (RNA recognition motif) domain and belongs to the splicing factor SR family. It is a sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. |
| Protein Interactions |
SUMO3; SUMO2; EED; CLK3; SRPK2; SRPK1; YWHAE; HNRNPA1; CDK6; YTHDC1; RBMX; RNPS1; SRSF10; NXF1; UBC; SRSF6; SRSF4; SRSF3; SRSF2; MAGOH; EIF4A3; BARD1; PAXIP1; PPP4R2; SF3B1; FAF2; PSIP1; GCN1L1; EIF4H; SRSF7; SRSF5; SRSF1; S100A9; RBMS2; RAN; PRKDC; NHP2L |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TRA2B (ARP40528_T100) antibody |
| Blocking Peptide |
For anti-TRA2B (ARP40528_T100) antibody is Catalog # AAP40528 (Previous Catalog # AAPP22295) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SFRS10 |
| Uniprot ID |
P62995 |
| Protein Name |
Transformer-2 protein homolog beta |
| Publications |
Fu, K. et al. Tra2beta protein is required for tissue-specific splicing of a smooth muscle myosin phosphatase targeting subunit alternative exon. J. Biol. Chem. 287, 16575-85 (2012). 22437831 |
| Sample Type Confirmation |
TRA2B is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_004584 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_004593 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TRA2B |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human Heart
 | Rabbit Anti-TRA2B Antibody
Catalog Number: ARP40528
Paraffin Embedded Tissue: Human cardiac cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | Human Jurkat
 | WB Suggested Anti-SFRS10 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateTRA2B is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
|
| Image 3 | Human Lung
 | Rabbit Anti-SFRS10 Antibody
Catalog Number: ARP40528
Paraffin Embedded Tissue: Human Lung
Cellular Data: Alveolar cells
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
