Product Number |
ARP40215_T100 |
Product Page |
www.avivasysbio.com/rpl8-antibody-c-terminal-region-arp40215-t100.html |
Name |
RPL8 Antibody - C-terminal region (ARP40215_T100) |
Protein Size (# AA) |
257 amino acids |
Molecular Weight |
28kDa |
NCBI Gene Id |
6132 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
ribosomal protein L8 |
Description |
|
Alias Symbols |
L8 |
Peptide Sequence |
Synthetic peptide located within the following region: KKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAM |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Kenmochi,N., (1998) Genome Res. 8 (5), 509-523 |
Description of Target |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
Protein Interactions |
TP53; HUWE1; SUMO2; TUBGCP3; CEP250; STAU1; UBC; MDM2; ZBTB1; EED; RPS25; RPL28; PARK2; FBXO6; UPF2; TARDBP; ICAM1; IGSF8; PAN2; ITGA4; IL7R; FN1; DPH3; UBL4A; VCAM1; EIF4A3; PA2G4; MAGOH; ESR1; RPLP0P6; RPL10L; TUBA1C; ATF7IP; RPL36; TXN2; PPT2; RPL23; R |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-RPL8 (ARP40215_T100) antibody |
Blocking Peptide |
For anti-RPL8 (ARP40215_T100) antibody is Catalog # AAP40215 (Previous Catalog # AAPP23487) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human RPL8 |
Uniprot ID |
P62917 |
Protein Name |
60S ribosomal protein L8 |
Publications |
Adenylyl cyclase A mRNA localized at the back of cells is actively translated in live chemotaxing Dictyostelium. J Cell Sci. 131, NULL (2018). 29618632
Wong, C. C., Traynor, D., Basse, N., Kay, R. R. & Warren, A. J. Defective ribosome assembly in Shwachman-Diamond syndrome. Blood 118, 4305-12 (2011). 21803848 |
Protein Accession # |
NP_000964 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_000973 |
Tested Species Reactivity |
Human |
Gene Symbol |
RPL8 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Yeast, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 93%; Zebrafish: 100% |
Image 1 | Human Lung
| Rabbit Anti-RPL8 Antibody Catalog Number: ARP40215 Paraffin Embedded Tissue: Human Lung Cellular Data: Alveolar cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
|
Image 2 | Human HepG2
| WB Suggested Anti-RPL8 Antibody Titration: 0.3125ug/ml Positive Control: HepG2 cell lysate |
|