Product Number |
ARP38957_T100 |
Product Page |
www.avivasysbio.com/aatf-antibody-n-terminal-region-arp38957-t100.html |
Name |
AATF Antibody - N-terminal region (ARP38957_T100) |
Protein Size (# AA) |
560 amino acids |
Molecular Weight |
63kDa |
NCBI Gene Id |
26574 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Apoptosis antagonizing transcription factor |
Alias Symbols |
DED, BFR2, CHE1, CHE-1 |
Peptide Sequence |
Synthetic peptide located within the following region: MAGPQPLALQLEQLLNPRPSEADPEADPEEATAARVIDRFDEGEDGEGDF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Lehner,B. (2004) Genome Res. 14 (7), 1315-1323 |
Description of Target |
The AATF is a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced apoptosis.The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. |
Protein Interactions |
MDM2; DAPK3; AR; HIPK2; NGDN; UBC; TSG101; LIN28A; MMS19; ZNF468; NEDD4L; WHSC1; SMAD3; EFNB3; CPD; UBD; CAND1; PIN1; SIRT7; SUMO2; CHEK2; RELA; tat; MAGED1; PCBD2; SS18L1; LZTR1; MPHOSPH6; POLR2J; MPP6; PAWR; DAZAP2; ATR; ATM; CHEK1; LDOC1; SP1; RB1; MAP |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-AATF (ARP38957_T100) antibody |
Blocking Peptide |
For anti-AATF (ARP38957_T100) antibody is Catalog # AAP38957 (Previous Catalog # AAPY00766) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human AATF |
Uniprot ID |
Q9NY61 |
Protein Name |
Protein AATF |
Sample Type Confirmation |
AATF is supported by BioGPS gene expression data to be expressed in Daudi |
Protein Accession # |
NP_036270 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_012138 |
Tested Species Reactivity |
Human |
Gene Symbol |
AATF |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93% |
Image 1 | Human Daudi
| WB Suggested Anti-AATF Antibody Titration: 5.0ug/ml ELISA Titer: 1:312500 Positive Control: Daudi cell lysateAATF is supported by BioGPS gene expression data to be expressed in Daudi |
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