NEUROD2 Antibody - C-terminal region (ARP38741_P050)

Data Sheet
 
Product Number ARP38741_P050
Product Page www.avivasysbio.com/neurod2-antibody-c-terminal-region-arp38741-p050.html
Name NEUROD2 Antibody - C-terminal region (ARP38741_P050)
Protein Size (# AA) 382 amino acids
Molecular Weight 41kDa
NCBI Gene Id 4761
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Neuronal differentiation 2
Alias Symbols NDRF, DEE72, EIEE72, bHLHa1
Peptide Sequence Synthetic peptide located within the following region: PGSRPTGHGLVFGSSAVRGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Westerman,B.A., et al., (2004) Biochim. Biophys. Acta 1676 (1), 96-103
Description of Target NEUROD2 is a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of NEUROD2 can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.
Protein Interactions TK1; PKN1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-NEUROD2 (ARP38741_P050) antibody
Blocking Peptide For anti-NEUROD2 (ARP38741_P050) antibody is Catalog # AAP38741 (Previous Catalog # AAPP20947)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human NEUROD2
Uniprot ID Q15784
Protein Name Neurogenic differentiation factor 2
Protein Accession # NP_006151
Purification Affinity Purified
Nucleotide Accession # NM_006160
Tested Species Reactivity Human
Gene Symbol NEUROD2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Image 1
Human Cerebellum
WB Suggested Anti-NEUROD2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human cerebellum
 

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