| Product Number |
ARP38578_T100 |
| Product Page |
www.avivasysbio.com/cbfa2t3-antibody-n-terminal-region-arp38578-t100.html |
| Name |
CBFA2T3 Antibody - N-terminal region (ARP38578_T100) |
| Protein Size (# AA) |
545 amino acids |
| Molecular Weight |
60kDa |
| NCBI Gene Id |
863 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| Alias Symbols |
ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3 |
| Peptide Sequence |
Synthetic peptide located within the following region: MPASRLRDRAASSASGSTCGSMSQTHPVLESGLLASAGCSAPRGPRKGGP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor. |
| Protein Interactions |
Zbtb38; Zbtb4; ZBTB33; GMEB2; SEC24A; MATN2; ZBTB47; UBC; RUNX1; TAL1; TRIM33; SIN3B; NCOR1; HDAC3; CBFA2T3; CBFA2T2; HDAC1; PRKAR2A; RUNX1T1; LDB1; TCF3; HDAC8; HDAC6; HDAC2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CBFA2T3 (ARP38578_T100) antibody |
| Blocking Peptide |
For anti-CBFA2T3 (ARP38578_T100) antibody is Catalog # AAP38578 (Previous Catalog # AAPP20768) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CBFA2T3 |
| Uniprot ID |
O75107 |
| Protein Name |
Protein CBFA2T3 |
| Sample Type Confirmation |
CBFA2T3 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
BAA31276 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_005187 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CBFA2T3 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-CBFA2T3 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysateCBFA2T3 is supported by BioGPS gene expression data to be expressed in Jurkat |
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