| Product Number |
ARP38543_T100 |
| Product Page |
www.avivasysbio.com/nrf1-antibody-c-terminal-region-arp38543-t100.html |
| Name |
NRF1 Antibody - C-terminal region (ARP38543_T100) |
| Protein Size (# AA) |
522 amino acids |
| Molecular Weight |
56kDa |
| NCBI Gene Id |
4899 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Nuclear respiratory factor 1 |
| Alias Symbols |
ALPHA-PAL |
| Peptide Sequence |
Synthetic peptide located within the following region: IVLSGETAAAVGALTGVQDANGLFMADRAGRKWILTDKATGLVQIPVSMY |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Chang,W.T., (2005) Biochem. Biophys. Res. Commun. 334 (1), 199-206 |
| Description of Target |
NRF1 is a phosphorylated nuclear protein with a bZIP domain. This protein homodimerizes and functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth.This gene encodes a phosphorylated nuclear protein with a bZIP domain. This protein homodimerizes and functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. |
| Protein Interactions |
POGZ; TRAF2; SP4; FHL2; DYNLL1; CSNK2B; CSNK2A1; UBC; HHV8GK18_gp81; CEBPB; PARP1; PPRC1; MAFF; PPARGC1A; Dynlt1b; CDK1; MRPL57; TFAM; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NRF1 (ARP38543_T100) antibody |
| Blocking Peptide |
For anti-NRF1 (ARP38543_T100) antibody is Catalog # AAP38543 (Previous Catalog # AAPP20734) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human NRF1 |
| Uniprot ID |
Q96AN2 |
| Protein Name |
NRF1 protein EMBL AAH16925.1 |
| Protein Accession # |
NP_005002 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_005011 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NRF1 |
| Predicted Species Reactivity |
Human, Rat |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100%; Rat: 91% |
| Image 1 | Human Lung
 | Human Lung |
| | Image 2 | Transfected 293T
 | WB Suggested Anti-NRF1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: Transfected 293T |
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