| Product Number |
ARP38386_T100 |
| Product Page |
www.avivasysbio.com/nr5a2-antibody-n-terminal-region-arp38386-t100.html |
| Name |
NR5A2 Antibody - N-terminal region (ARP38386_T100) |
| Protein Size (# AA) |
541 amino acids |
| Molecular Weight |
61kDa |
| NCBI Gene Id |
2494 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Nuclear receptor subfamily 5, group A, member 2 |
| Alias Symbols |
B1F, CPF, FTF, B1F2, LRH1, LRH-1, FTZ-F1, hB1F-2, FTZ-F1beta |
| Peptide Sequence |
Synthetic peptide located within the following region: MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGY |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lee,Y.K., (2006) J. Biol. Chem. 281 (12), 7850-7855 |
| Description of Target |
NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development. |
| Protein Interactions |
NSD1; NCOA1; CREB1; UBE2I; RAD54L2; NR0B2; GPS2; ILF3; PNRC2; COPS5; PNRC1; BCKDK; NRIP1; SRC; NPPA; FTH1; ALB; SUMO1; PPARGC1A; POLR2D; EDF1; SMARCD3; PROX1; Ncoa3; Ptpn6; CTNNB1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NR5A2 (ARP38386_T100) antibody |
| Blocking Peptide |
For anti-NR5A2 (ARP38386_T100) antibody is Catalog # AAP38386 (Previous Catalog # AAPP20572) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human NR5A2 |
| Uniprot ID |
O00482 |
| Protein Name |
Nuclear receptor subfamily 5 group A member 2 |
| Protein Accession # |
NP_995582 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_205860 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NR5A2 |
| Predicted Species Reactivity |
Human, Rat, Cow, Guinea Pig, Pig, Sheep |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Guinea Pig: 86%; Human: 100%; Pig: 92%; Rat: 93%; Sheep: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-NR5A2 Antibody Titration: 2.5ug/ml
Positive Control: HepG2 cell lysate |
|
