| Product Number |
ARP38232_T100 |
| Product Page |
www.avivasysbio.com/sox2-antibody-n-terminal-region-arp38232-t100.html |
| Name |
SOX2 Antibody - N-terminal region (ARP38232_T100) |
| Protein Size (# AA) |
317 amino acids |
| Molecular Weight |
34kDa |
| NCBI Gene Id |
6657 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
SRY (sex determining region Y)-box 2 |
| Alias Symbols |
ANOP3, MCOPS3 |
| Peptide Sequence |
Synthetic peptide located within the following region: AAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lei,J.X., (2005) Cell Death Differ. 12 (11), 1368-1377 |
| Description of Target |
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). |
| Protein Interactions |
SUMO1; DMAP1; TBX2; SETD7; FAM21A; FZR1; MMS19; MRPS35; ZNF462; LSM2; CCAR2; MIER1; ZDBF2; CHD8; EP400; TSHZ3; RANBP10; ZNF687; XPO5; INTS2; MTA3; CORO1B; CASC5; MRPS22; KCMF1; MEPCE; TRERF1; INTS9; PARVA; SCYL2; CHD7; ZCCHC8; SOX6; BRIX1; SAMD4B; GID8; C |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SOX2 (ARP38232_T100) antibody |
| Blocking Peptide |
For anti-SOX2 (ARP38232_T100) antibody is Catalog # AAP38232 (Previous Catalog # AAPP10741) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SOX2 |
| Uniprot ID |
P48431 |
| Protein Name |
Transcription factor SOX-2 |
| Protein Accession # |
NP_003097 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_003106 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SOX2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Goat, Pig, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Goat: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human Hela
 | Host: Rabbit
Target Name: SOX2
Sample Tissue: Human Hela
Antibody Dilution: 1.0ug/ml |
|
