PLAG1 Antibody - C-terminal region (ARP38178_P050)

• Product Number: ARP38178_P050
• Name: PLAG1 Antibody - C-terminal region (ARP38178_P050)
• Protein Size (# AA): 500 amino acids
• Molecular Weight: 56kDa
• NCBI Gene Id: 5324
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Pleiomorphic adenoma gene 1
• Alias Symbols: PSA, SGPA, SRS4, ZNF912
• Peptide Sequence: Synthetic peptide located within the following region: SSVSQLPPQTQDLQDPANTIGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Persson,F., (2008) Oncogene 27 (21), 3072-3080
• Description of Target: PLAG1 is a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.
• Protein Interactions: SMAD3; ALB; PIAS4; PIAS2; PIAS1; SUMO1; KPNA2;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-PLAG1 (ARP38178_P050) antibody is Catalog # AAP38178 (Previous Catalog # AAPP20354)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PLAG1
• Uniprot ID: Q6DJT9
• Protein Name: Zinc finger protein PLAG1
• Protein Accession #: NP_002646
• Purification: Affinity Purified
• Nucleotide Accession #: NM_002655
• Tested Species Reactivity: Human
• Gene Symbol: PLAG1
• Predicted Species Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%
• Image 1: Human Fetal Muscle
  
  Host: Rabbit
  Target Name: PLAG1
  Sample Type: Human Fetal Muscle
  Antibody Dilution: 1.0ug/ml
• Image 2: Human Fetal Lung
  
  Host: Rabbit
  Target Name: PLAG1
  Sample Type: Human Fetal Lung
  Antibody Dilution: 1.0ug/ml
• Image 3: Human OVCAR-3
  
  WB Suggested Anti-PLAG1 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:312500
  Positive Control: OVCAR-3 cell lysate