| Product Number |
ARP38013_T100 |
| Product Page |
www.avivasysbio.com/prdm1-antibody-n-terminal-region-arp38013-t100.html |
| Name |
PRDM1 Antibody - N-terminal region (ARP38013_T100) |
| Protein Size (# AA) |
789 amino acids |
| Molecular Weight |
88kDa |
| NCBI Gene Id |
639 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
PR domain containing 1, with ZNF domain |
| Alias Symbols |
BLIMP1, PRDI-BF1 |
| Peptide Sequence |
Synthetic peptide located within the following region: MKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAEASLPRN |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Miyajima,N., et al., (2006) J. Immunol. 176 (7), 4042-4050 |
| Description of Target |
PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. |
| Protein Interactions |
PRMT5; SENP1; EHMT2; PIAS1; SUMO1; IRF2; IRF1; HDAC2; HDAC1; HIST1H1A; MS4A1; HSP90AA1; ATXN1; ELAVL1; KDM1A; IRF4; TLE2; TLE1; AES; PRMT7; HIST2H3A; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PRDM1 (ARP38013_T100) antibody |
| Blocking Peptide |
For anti-PRDM1 (ARP38013_T100) antibody is Catalog # AAP38013 (Previous Catalog # AAPP20186) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human PRDM1 |
| Uniprot ID |
O75626 |
| Protein Name |
PR domain zinc finger protein 1 |
| Protein Accession # |
NP_001189 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001198 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PRDM1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-PRDM1 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate |
|
