| Product Number |
ARP37717_T100 |
| Product Page |
www.avivasysbio.com/ddx46-antibody-c-terminal-region-arp37717-t100.html |
| Name |
DDX46 Antibody - C-terminal region (ARP37717_T100) |
| Protein Size (# AA) |
1031 amino acids |
| Molecular Weight |
113kDa |
| NCBI Gene Id |
9879 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 |
| Alias Symbols |
Prp5, PRPF5 |
| Peptide Sequence |
Synthetic peptide located within the following region: GERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Xu,Y.Z., et al., (2004) EMBO J. 23 (2), 376-385 |
| Description of Target |
DDX46 is a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX46 is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. |
| Protein Interactions |
HUWE1; UBC; RPA3; RPA2; RPA1; PRPF40A; APBB1; SRPK2; LMNA; TPM2; PNLIPRP2; SMIM20; GEMIN5; SF3A3; SRSF11; CUL3; SIRT7; SF3A2; ELAVL1; SUMO2; Sf3a1; TCEA1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-DDX46 (ARP37717_T100) antibody |
| Blocking Peptide |
For anti-DDX46 (ARP37717_T100) antibody is Catalog # AAP37717 (Previous Catalog # AAPP09049) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human DDX46 |
| Uniprot ID |
Q7L014 |
| Protein Name |
Probable ATP-dependent RNA helicase DDX46 |
| Sample Type Confirmation |
DDX46 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_055644 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_014829 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
DDX46 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-DDX46 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:12500
Positive Control: Jurkat cell lysateDDX46 is supported by BioGPS gene expression data to be expressed in Jurkat |
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