PUS1 Antibody - C-terminal region (ARP37261_P050)

• Product Number: ARP37261_P050
• Name: PUS1 Antibody - C-terminal region (ARP37261_P050)
• Protein Size (# AA): 423 amino acids
• Molecular Weight: 48kDa
• NCBI Gene Id: 56361
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Pseudouridine synthase 1
• Alias Symbols: MPU, MPUS1, mPus1p, A730013B20Rik
• Peptide Sequence: Synthetic peptide located within the following region: PTIVSTERDERSMAQWLNTLPIHNFSGTALGAADTGAKVPSSLEGSEGDG
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Zhao,X., et al., (2004) Mol. Cell 15 (4), 549-558
• Description of Target: Pus1 converts specific uridines to PSI in a number of tRNA substrates. Pus1 acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Pus1 is involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA.
• Protein Interactions: Rarg; Sra1; Rarb;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-PUS1 (ARP37261_P050) antibody is Catalog # AAP37261 (Previous Catalog # AAPP20143)
• Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse
• Uniprot ID: Q791J1
• Protein Name: tRNA pseudouridine synthase A, mitochondrial
• Protein Accession #: NP_001020733
• Purification: Affinity Purified
• Nucleotide Accession #: NM_001025562
• Tested Species Reactivity: Mouse
• Gene Symbol: PUS1
• Predicted Species Reactivity: Human, Mouse, Rat
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Human: 92%; Mouse: 100%; Rat: 100%
• Image 1: Mouse SP2/0
  
  WB Suggested Anti-PUS1 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:312500
  Positive Control: SP2/0 cell lysate