| Product Number |
ARP36681_T100 |
| Product Page |
www.avivasysbio.com/ibsp-antibody-n-terminal-region-arp36681-t100.html |
| Name |
IBSP Antibody - N-terminal region (ARP36681_T100) |
| Protein Size (# AA) |
317 amino acids |
| Molecular Weight |
35kDa |
| NCBI Gene Id |
3381 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Integrin-binding sialoprotein |
| Alias Symbols |
BSP, BNSP, SP-II, BSP-II |
| Peptide Sequence |
Synthetic peptide located within the following region: SATTLGYGEDATPGTGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Barnes,G.L., et al., (2003) Cancer Res. 63 (10), 2631-2637 |
| Description of Target |
The protein encoded by the IBSP gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-IBSP (ARP36681_T100) antibody |
| Blocking Peptide |
For anti-IBSP (ARP36681_T100) antibody is Catalog # AAP36681 (Previous Catalog # AAPP08108) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human IBSP |
| Uniprot ID |
P21815 |
| Protein Name |
Bone sialoprotein 2 |
| Protein Accession # |
NP_004958 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_004967 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
IBSP |
| Predicted Species Reactivity |
Human, Dog |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 79%; Human: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-IBSP Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate |
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