Product Number |
ARP36583_T100 |
Product Page |
www.avivasysbio.com/anxa6-antibody-n-terminal-region-arp36583-t100.html |
Name |
ANXA6 Antibody - N-terminal region (ARP36583_T100) |
Protein Size (# AA) |
673 amino acids |
Molecular Weight |
74kDa |
NCBI Gene Id |
309 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Annexin A6 |
Alias Symbols |
p68, p70, ANX6, CBP68, CPB-II |
Peptide Sequence |
Synthetic peptide located within the following region: ALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYE |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Cuschieri,J., et al., (2005) Surgery 138 (2), 158-164 |
Description of Target |
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. |
Protein Interactions |
UBC; MDM2; THOP1; PLS3; MTAP; IDH1; HPRT1; GOT1; ADSS; POLE3; NAMPT; UBE2H; ATP4A; METTL18; MLH1; SNCA; CUL5; SIRT7; PRKCA; TJP1; CD4; H2AFX; CDC73; TPD52; S100B; S100A1; RASA1; CR2; A2M; tax; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ANXA6 (ARP36583_T100) antibody |
Blocking Peptide |
For anti-ANXA6 (ARP36583_T100) antibody is Catalog # AAP36583 (Previous Catalog # AAPP07816) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA6 |
Uniprot ID |
P08133 |
Protein Name |
Annexin A6 |
Sample Type Confirmation |
ANXA6 is supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_001146 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001155 |
Tested Species Reactivity |
Human |
Gene Symbol |
ANXA6 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 86%; Guinea Pig: 85%; Horse: 86%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 85%; Rat: 93%; Zebrafish: 93% |
Image 1 | Human Jurkat
| WB Suggested Anti-ANXA6 Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysateANXA6 is supported by BioGPS gene expression data to be expressed in Jurkat |
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