| Product Number |
ARP34452_P050 |
| Product Page |
www.avivasysbio.com/vps24-antibody-n-terminal-region-arp34452-p050.html |
| Name |
VPS24 Antibody - N-terminal region (ARP34452_P050) |
| Protein Size (# AA) |
222 amino acids |
| Molecular Weight |
25kDa |
| NCBI Gene Id |
51652 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Charged multivesicular body protein 3 |
| Alias Symbols |
NEDF, VPS24, CGI-149 |
| Peptide Sequence |
Synthetic peptide located within the following region: RVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Whitley,P., et al., (2003) J Biol Chem. 278(40), 38786-95 |
| Description of Target |
VPS24 encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. |
| Protein Interactions |
STAMBP; SMAD5; SMAD1; ATP6V1B1; APP; UBD; CHMP4B; CHMP3; CHMP2A; CHMP2B; TNPO3; RAB11A; CHMP4A; VAV2; UBC; VTA1; VPS4A; IGFBP7; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CHMP3 (ARP34452_P050) antibody |
| Blocking Peptide |
For anti-CHMP3 (ARP34452_P050) antibody is Catalog # AAP34452 (Previous Catalog # AAPY00414) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human VPS24 |
| Uniprot ID |
Q3ZTS9 |
| Protein Name |
Charged multivesicular body protein 3 |
| Protein Accession # |
NP_057163 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_016079 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CHMP3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human HepG2
 | WB Suggested Anti-VPS24 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysate |
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