| Product Number |
ARP34151_T100 |
| Product Page |
www.avivasysbio.com/atf2-antibody-c-terminal-region-arp34151-t100.html |
| Name |
ATF2 Antibody - C-terminal region (ARP34151_T100) |
| Protein Size (# AA) |
505 amino acids |
| Molecular Weight |
55kDa |
| NCBI Gene Id |
1386 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Activating transcription factor 2 |
| Alias Symbols |
HB16, CREB2, TREB7, CREB-2, CRE-BP1 |
| Peptide Sequence |
Synthetic peptide located within the following region: LRNEVAQLKQLLLAHKDCPVTAMQKKSGYHTADKDDSSEDISVPSSPHTE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Kravets,A., et al., (2004) J. Biol. Chem. 279 (19), 19916-19923 |
| Description of Target |
ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. |
| Protein Interactions |
MAPK10; MAPK9; MAPK8; MAPK1; SUMO1; KIFC3; FOS; MAPK14; EXOSC8; JUN; CREBBP; ATF2; CEBPG; BACH1; ATF4; ATF3; BATF3; DDIT3; BATF; FOSL1; H2AFY; RB1; GAPDH; NME2P1; TUBB; SFXN1; RAB2B; TMX1; GRPEL1; COLGALT1; AHNAK; SQRDL; RTN4; APMAP; C19orf10; RAB14; ERO1 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ATF2 (ARP34151_T100) antibody |
| Blocking Peptide |
For anti-ATF2 (ARP34151_T100) antibody is Catalog # AAP34151 (Previous Catalog # AAPP05413) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human ATF2 |
| Uniprot ID |
P15336-2 |
| Protein Name |
Cyclic AMP-dependent transcription factor ATF-2 |
| Protein Accession # |
NP_001871 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001880 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
ATF2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Mouse Testis
 | Host: Mouse
Target Name: ATF2
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml |
|
| Image 2 | Human Jurkat
 | WB Suggested Anti-ATF2 Antibody Titration: 1.25ug/ml
Positive Control: Jurkat cell lysate |
|
| Image 3 | Human kidney
 | Human kidney |
|
| Image 4 | Human Intestine
 | Human Intestine |
|
| Image 5 | Human Ovary
 | Rabbit Anti-ATF2 Antibody
Catalog Number: ARP34151_T100
Formalin Fixed Paraffin Embedded Tissue: Human Ovary Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
